Table 1

Allele-specific splicing candidates.

Gene

Exon Included Reads (B6:CAST)

Exon Skipped Reads (B6:CAST)

p(ASE) is less than*

Gene function (Gene Ontology)

Conserved protein domain encoded by skipped exon (Pfam)


Slc8a1

6 (2:4)

429 (232:197)

0.344

reduction of cytosolic calcium ion concentration

No domain reported

Baz2b

30 (9:21)

99 (58:41)

0.021

chromatin modification

Bromodomain adj. to zinc finger domain (PTHR22880)

Eif4enif1

24 (3:21)

18 (12:6)

0.119

protein transport

No domain reported

Epb4.1l2

7 (5:2)

6 (2:4)

0.344

cortical actin cytoskeleton organization

4.1 C-terminal domain (PF05902)

Papd4

6 (6:0)

3 (0:3)

0.125

polynucleotide adenylyltransferase activity

PAP/OAS1 substrate-binding domain (SSF81631))

Aqr

8 (8:0)

3 (0:3)

0.125

RNA splicing; body morphogenesis

DNA2/NAM7 helicase family member (PTHR10887:SF5)

Ankrd12

32 (9:23)

3 (3:0)

0.125

unknown

Ankyrin repeat (SSF48403)

Nudc

27 (11:16)

75 (75:0)

0.221

nuclear migration; nervous system development

CS (PS51203), HSP20-like chaperones (SSF49764)

Rbm17

32 (16:16)

5 (5:0)

0.031

mRNA processing, RNA binding

Splicing factor 45 (PTHR13288:SF9)

Cacna1h

1118 (378:740)

5 (5:0)

0.031

Calcium transport

Voltage-gated_potassium_channels (SSF81324)


Babak et al. BMC Genomics 2010 11:473   doi:10.1186/1471-2164-11-473

Open Data