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Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation

Tomas Babak1, Philip Garrett-Engele1, Christopher D Armour26, Christopher K Raymond26, Mark P Keller3, Ronghua Chen1, Carol A Rohl1, Jason M Johnson1, Alan D Attie3, Hunter B Fraser24* and Eric E Schadt25*

Author Affiliations

1 Merck Research Laboratories, Research Informatics, 33 Avenue Louis Pasteur, Boston, MA, 02115, USA

2 Rosetta Inpharmatics, LLC, a wholly owned subsidiary of Merck & Co., Inc., 401 Terry Ave N, Seattle, WA, 98109, USA

3 University of Wisconsin-Madison, Department of Biochemistry, 433 Babcock Drive, Madison, WI, 53706, USA

4 Currently at Department of Biology, Stanford University, 371 Serra Mall, Stanford, CA, 94305, USA

5 Currently at Pacific Biosciences, 1505 Adams Drive, Menlo Park, CA, 94025, USA

6 Currently at NuGEN Technologies, 201 Industrial Road, San Carlos, CA 94070, USA

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BMC Genomics 2010, 11:473  doi:10.1186/1471-2164-11-473

Published: 13 August 2010

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Supplemental Material. Supplemental Figures, Tables, Methods, and Discussion Supplement

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