Additional file 8.
Response of putative TOP mRNAs to insulin stimulation in cardiomyocytes (Microsoft Excel Spreadsheet). Neonatal rat cardiomyocytes were exposed to insulin (50 mU/ml, 1 h) or ET-1 (100 nM, 1 h) or left unstimulated (controls). Total and polysomal RNA prepared were analysed using Affymetrix rat genome 230 2.0 microarrays. Probesets corresponding to TOP mRNAs identified by Yameshita et al. (Nuclei Acids Res. (2008) 36:3707-3715) were identified and the microarray data mined for the cardiomyocyte response. Results are the mean fold change (n = 4) in response to insulin or ET-1 relative to controls. Mean raw fluorescence values are given for the controls.
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Markou et al. BMC Genomics 2010 11:343 doi:10.1186/1471-2164-11-343