Figure 7.

Variation information for rs2476601. A search for diabetes in the Ensembl main page shows 16,009 human variations associated with this disease in the NHGRI GWAS catalogue. Searching for one of these, rs2476601, and then clicking on this hit, opens the variation tab for this SNP. The phenotype data link at the left ([62]shown in the figure) reveals this variation is implicated in several diseases, including Rheumatoid Arthritis and Crohn's Disease. Links to the GWAS catalogue entries are displayed along with studies in the PubMed database that show the associations. The risk alleles for these diseases are not the same, revealing this position in the genome to be potentially highly important for function.

Spudich and Fern├índez-Su├írez BMC Genomics 2010 11:295   doi:10.1186/1471-2164-11-295
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