Table 3

Altered levels of miRNA biogenesis and miRISC components in K562 and HL60.

Protein

Function

K562/Normal

(Fold Change)

HL60/Normal

(Fold Change)


DROSHA (RNASEN)

PrimiRNA processing

2.238954

2.017825

DGCR8

PrimiRNA processing

2.078018

Unchanged

XPO5

Exporting premiRNA

2.669646

2.199101

RAN

Exporting premiRNA

1.832214

Unchanged

DICER1

PremiRNA processing

-1.79971

Unchanged


Vaz et al. BMC Genomics 2010 11:288   doi:10.1186/1471-2164-11-288

Open Data