Probabilistic genetic interaction networking. Genetic interaction networks predicted for Caenorhabditis elegans orthologues of expressed sequence tags (ESTs) unique to either the ensheathed (= L3) (a) or exsheathed (= xL3) (b) larval stage of Haemonchus contortus (see Methods); Representing L3: ced-10 was linked to axon guidance; krs-1 to lysine biosynthesis; pas-4 and pas-5 to the proteasome system; cul-3, elc-1 and smo-1 to ubiquitin; F21D5.7 to protein export; rpl-5, rps-14, rpl-24.1, rpl-32 and Y37E3.8a to ribosome. Representing xL3: F57B10.3a was linked to glycolysis; ncs-1 to olfactory signal transduction; cpr-6 to antigen processing and presentation.
Cantacessi et al. BMC Genomics 2010 11:266 doi:10.1186/1471-2164-11-266