Application of in silico and experimental masks. MvA plots comparing expression differences with expression averages for all transcript clusters. Expression signals from ALL-16 xenografts ALL.100 (100% human) (n = 8) versus ALL.90 (90% human) (n = 3) were compared following the application of the A experimental B in silico or C combined masking approaches. Transcript clusters identified as susceptible to cross-species hybridisation are shown in black (.) all others are grey (.). Plots were generated using RMA normalised log2 signal intensities, lines represent 2-fold difference (log2 = 1).
Samuels et al. BMC Genomics 2010 11:256 doi:10.1186/1471-2164-11-256