Research article
Genome response to tissue plasminogen activator in experimental ischemic stroke
-
* Corresponding author: Glen C Jickling gcjickling@ucdavis.edu
1 Department of Neurology and M.I.N.D. Institute, University of California at Davis, Sacramento, California 95817, USA
2 Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, 90048, USA
BMC Genomics 2010, 11:254 doi:10.1186/1471-2164-11-254
Published: 21 April 2010Additional files
Additional file 1:
List of genes regulated by tPA in rat ischemic stroke. The 929 gene probes differentially regulated by tPA in rats with ischemic stroke (p ≤ 0.05, fold change ≥ |1.2|.
Format: XLS Size: 152KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 2:
List of genes regulated by tPA in reperfused-MCAO. The 533 genes probes differentially regulated by tPA at 24 hours in rats with reperfused-MCAO, (p ≤ 0.01, fold change ≥ |1.2|).
Format: XLS Size: 95KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 3:
List of genes predictive of tPA treatment in reperfused-MCAO. The 27 gene probes identified to optimally predict treatment with tPA in rats with reperfused-MCAO. The 27 probes were derived from the 533 gene probes in Additional File 2 using Prediction Analysis of Microarrays (PAM).
Format: XLS Size: 19KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 4:
List of genes regulated by tPA in permanent-MCAO. The 293 gene probes differentially regulated by tPA at 24 hours in rats with permanent-MCAO (p ≤ 0.01, fold change ≥ |1.2|)
Format: XLS Size: 58KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 5:
List of genes predictive of tPA treatment in permanent-MCAO. The 62 gene probes identified to optimally predict treatment with tPA in rats with permanent-MCAO. The 62 probes were derived from the 293 gene probes in Additional File 4 using Prediction Analysis of Microarrays (PAM).
Format: XLS Size: 23KB Download file
This file can be viewed with: Microsoft Excel Viewer