Open Access Highly Accessed Methodology article

DNA copy number, including telomeres and mitochondria, assayed using next-generation sequencing

John C Castle12*, Matthew Biery13, Heather Bouzek14, Tao Xie15, Ronghua Chen16, Kira Misura17, Stuart Jackson16, Christopher D Armour13, Jason M Johnson16, Carol A Rohl16 and Christopher K Raymond13*

Author Affiliations

1 Rosetta Inpharmatics LLC, a wholly owned subsidiary of Merck & Co., Inc., Seattle, Washington 98109, USA

2 Institute for Translational Oncology and Immunology (TrOn), Mainz, Germany

3 NuGEN Technologies, Inc., Seattle, Washington, USA

4 University of Washington, Seattle, Washington, USA

5 Pfizer, Inc., San Diego, California, USA

6 Merck Research Laboratories, Boston, Massachusetts, USA

7 Amgen, Inc., Seattle, Washington, USA

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BMC Genomics 2010, 11:244  doi:10.1186/1471-2164-11-244

Published: 16 April 2010

Additional files

Additional file 1:

Figure S1. UMC-11 chromosome 9 copy number from the deep-sequencing platform (top) and Affymetrix SNP6 arrays and the Sanger Picnic algorithm [13] (bottom, green line).

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Additional file 2:

Figure S2. UMC-11 chromosome 12 copy number from the deep-sequencing platform (top) and Affymetrix SNP6 arrays with the Sanger Picnic algorithm [13] (bottom, green line).

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