Table 1

The ALT, AST, STB and LDH levels in mouse serum after ConA administration

ALT

AST

STB

LDH

Control group

38.33 ± 1.53

85.33 ± 4.04

2 ± 0

832.67 ± 94.00

1 h

64.67 ± 7.51Δ

194.67 ± 60.90Δ

3.67 ± 0.58Δ

980.0 ± 197.38

3 h

66.67 ± 12.50Δ

222.38 ± 113.40

3 ± 1.00

2454.78 ± 198.62

6 h

1068.17 ± 418.08

768.0 ± 729.61Δ

4.83 ± 0.60Δ

3514.33 ± 977.57Δ*

ΔCompared with control, P < 0.05, *compared with 1 h, P < 0.05

The serum markers of liver injury, such as ALT, AST, STB and LDH, increased with time after ConA injection. Compared with normal control, ALT and STB increased at 1 h by 1.7-fold and 1.8-fold respectively, and ALT, AST, STB and LDH level at 6 h increased by 27.9-fold, 9.0-fold, 2.4-fold and 4.2-fold, respectively.

Chen et al. BMC Genomics 2010 11:240   doi:10.1186/1471-2164-11-240