Research article
Evolutionary conservation of essential and highly expressed genes in Pseudomonas aeruginosa
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* Corresponding author: Susanne Häussler susanne.haeussler@helmholtz-hzi.de
1 Chronic Pseudomonas Infections Research Group, Helmholtz-Center for Infection Research, Braunschweig, Germany
2 Department of Genome Research, Helmholtz-Center for Infection Research, Braunschweig, Germany
3 Project Group Bioinformatics and Statistics, Helmholtz-Center for Infection Research, Braunschweig, Germany
4 Department of Computer Science, University of Applied Sciences Braunschweig/Wolfenbüttel, Wolfenbüttel, Germany
5 Twincore, Center for Experimental and Clinical Infection Research, joint venture of the Helmholtz Center for Infection Research and the Medical School Hannover, Hannover, Germany
BMC Genomics 2010, 11:234 doi:10.1186/1471-2164-11-234
Published: 9 April 2010Additional files
Additional file 1:
Overview of the clinical strains included in the sequenced pools. This table specifies the strains that were merged in the three sequence pools and their clinical source.
Format: XLS Size: 21KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 2:
Complete list of proteins with full conservation of the amino acid sequence. All 980 genes identified to show no sequence variation at the protein level (nonsynonymous substitution rate dN = 0) in all three sequence pools are listed in this xls file. Additional information includes gene annotation, experimental essentiality, phylogenetic distribution of orthologs and effect on antibiotic susceptibility.
Format: XLS Size: 213KB Download file
This file can be viewed with: Microsoft Excel Viewer