RT-PCR confirmation of age-related changes of cell cycle and apoptosis genes. A RT-PCR (cancer) SuperArray of 84 cell cycle and apoptosis genes was used to compare mRNA from 2m and 26m mouse MSCs. The analysis confirms 2-fold and 50-fold decrease of p53 and p21 respectively and significant decrease of apoptosis transcripts with age.
Wilson et al. BMC Genomics 2010 11:229 doi:10.1186/1471-2164-11-229