Table 4

Number of significant GSEA gene sets in Coriell-18, ECACC-6 and Nf1-Mouse-12 expression datasets.

Coriell-18

ECACC-6

Nf1-Mouse-12


Up-regulated gene sets

4

65

189

Down-regulated gene sets

40

1

4


Gene sets with FDR < 0.05 were considered significant. "Up-regulated gene sets" and "Down-regulated gene sets" designate GSEA gene sets overexpressed or underexpressed, respectively, in NF1-affected individuals or Nf1+/- mice as compared to NF1-unaffecteds or wild-type mice.

Pemov et al. BMC Genomics 2010 11:194   doi:10.1186/1471-2164-11-194

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