Primary nitrogen assimilation and glutamate metabolism. Simplified schematic representation of the pathways leading to the synthesis and the conversion of glutamate and the way they are affected in the glu1-2 mutant. Only the data related to glu1-2 leaves is depicted. Colour code: blue are upregulated, red are downregulated, violet are both up- and downregulated steps whereas grey are unaffected steps of these pathways. Enzymes: (1) nitrate reductase, (2) nitrite reductase, (3) glutamine synthetase, (4) NADH-GOGAT, (5) Fd-GOGAT, (6) asparagine synthase, (7) asparaginase, (8) aspartate aminotransferase, (9) alanine:2-oxoglutarate aminotransferase, (10) glutamate:glyoxylate aminotransferase, (11) glycine decarboxylase complex, (12) serine hydroxymethyltransferase, (13) glutamate decarboxylase, (14) γ-aminobutyric acid transaminase, (15) succinic semialdehyde dehydrogenase, (16) glutamate-cysteine ligase, (17) glutathione synthetase, (18) glutamate dehydrogenase, (19) acetohydroxyacid synthase, (20) ketolacid reductoisomerase, (21) dehydroxyacid dehydratase, (22) branched-chain aminotransferase. Subcellular compartmentalisation is not taken into account in this figure and reductants are only indicated for some of the reactions. The detailed data of the genes depicted in this figure and related data for genes affected in glu1-2 roots is presented in Table 2.
Kissen et al. BMC Genomics 2010 11:190 doi:10.1186/1471-2164-11-190