Clustering and structure of DLPs. A. Clustering analysis of the sequences in Figure 1 by the CLUSTAL program. Cyan and purple branches respectively represent CITDs, and nasonins and related peptides. Nasonin-2 and nasonin-6 are aligned as repeated domains; B. Structural models of DLPs from N.vitripennis. Navidefensin1-1 and navidefensin2-1 modeled ab initio by I-TASSER are shown in ribbon displayed by MolMol. Superimposition of these two structures shows an extra carboxyl-terminal domain in navidefensin1-1 structure. The model structure of nasonin-1 is compared with those of sapecin, termicin and cobatoxin.
Tian et al. BMC Genomics 2010 11:187 doi:10.1186/1471-2164-11-187