Additional file 5.

Bacilysin containing island from Alcoy genome. Bacilysin cluster begins with an ORF homolog of a phospho-2-dehydro-3-deoxyheptonate aldolase, which is an intermediate of the synthesis of chorismate (lpa03410); the next four ORFs are homologs of bacilysin biosynthesis BacA (lpa03409), BacB (lpa03408), BacC (lpa03407) and BacC (lpa03406); lpa03405 is a transporter of the multidrug/metabolite exporter family; lpa0304 is a purine metabolism-related protein. lpa03404 and lpa3403 are related to chorismate mutase and the subsequent amino-transferase could be related to the final steps in bacilysin biosynthesis [61]. Located further along the island, lpa03412 is a homolog of an S24-like peptidase, followed by two hypothetical proteins and a bacteriocin adenylyltransferase (lpa03416). The PR5 island ends with an IS10-related transposase, lpa03419, two hypothetical proteins and a phage related integrase (lpa03425). This island demonstrates evidence of cluster acting in bacilysin-like bacteriocin production that is specific to the Alcoy genome.

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D'Auria et al. BMC Genomics 2010 11:181   doi:10.1186/1471-2164-11-181