Table 3

Classification of H. mustelae outer membrane proteins in relation to H. pylori OMPs

Gene

Protein length (AA)

Predicted MW (Da)

N-terminal signal motif

C-term motif

FASTA Smith-Waterman identity*

Detected in proteome


Hof-related OMPs

HMU05640

456

51,804

A?MDF

-YSF

32.1% in 479 aa overlap with H. pylori HofB (HP1083)

Yes

HMU05650

451

51,181

A?VET

-YGF

36.2% in 496 aa overlap with H. pylori HofF (HP0788)

Yes

HMU10680

447

50,681

A?ASS

-YFF

29.3% in 474 aa overlap with H. pylori HofE (HP0782)

No

Hop-related OMP

HMU04150

189

20,863

R?AYD?

-YSF

34.7% in 170 aa overlap with HP0608

No

FecA-related OMP

HMU11950

220

25,230

?

-ENP

No significant homologues

No

Unclassified OMPS

HMU00140

232

26,345

G↓AGT

-FLF

No significant homologues

No

HMU00150

252

28,374

A↓KED

-IIF

No significant homologues

No

HMU00180

242

27,650

unclear

-YVF

No significant homologues

No

HMU00690

208

22,360

A↓EAI

-YTF

No significant homologues

No

HMU00810

135

15,492

A↓LVD

-IRY

No significant homologues

No

HMU01060

316

34,414

E↓ATK

-WYF

39.7% in 194 aa overlap with HomD (HP1453)

No

HMU02490

469

51,412

A↓GKL

-YNF

No significant homologues

No

HMU03240

394

32,308

A↓IEN

-FYF

34.5 in 281 aa overlap with HP0726

No

HMU03280

282

25,467

unclear

-KFF

No significant homologues

No

HMU03510

162

17,686

V↓SPE

-VEF

No significant homologues

No

HMU04930

899

98,821

A↓YNP?

-WVF

27.2% in 913 aa overlap with HomC (HP0373)

No

HMU07910

873

98,252

A↓NEI

-YHF

32.0% in 443 aa overlap with HofD (HP0487)

No

HMU09930

565

62,131

V↓AGA

-YHW

55% in 586 aa overlap with OmpP1 (HP0839)

No

HMU13480

258

28,279

A↓TKG?

-LIY

32.0% in 259 aa overlap with HH_1629

No

HMU13600

190

21,548

A↓MTL

-EAK

No significant homologues

Yes

HMU13670

173

19,128

A↓KTC

-NIK

No significant homologues

Yes

HMU13270

236

27,193

-NHL

No significant homologues

No

HMU00260

196

21,989

A↓HAR?

-FVF

No significant homologues

No

HMU07990

343

39,155

A↓ENL

-FAF

42.9% in 233 aa overlap with HP0694

No

HMU10040

167

18,839

-EGK

50.9% in 163 aa overlap with HP1546

No

HMU01230

232

24,626

A↓NTN

-YKF

44.5% in 236 aa overlap with HH_0525

No


† Predicted by SignalP 2.0 HMM with confidence, with low confidence (?), or not predicted (unclear).

*Only homologies with E-value <10-10 presented.

O'Toole et al. BMC Genomics 2010 11:164   doi:10.1186/1471-2164-11-164

Open Data