Promoter analysis of hypoxia related gene signatures obtained from MSigDB using the -1500,+500 portions of the promoters and 105 re-samples for estimations of PE and PP. A) Results for the MENSE_HYPOXIA_UP signature. B) Results for the HIF_TARGETS signature. C) Results for the HYPOXIA_NORMAL_UP signature. Insert, motifs with maximum -Log(PE) and -Log(PP) values. D) Results for the MANALO_HYPOXIA_UP signature. All signature designations are as in MSigDB.
Veerla et al. BMC Genomics 2010 11:145 doi:10.1186/1471-2164-11-145