Identification of a common gene response induced by the 3 treatments. A. The 30 common genes up-regulated more than 2.5 fold by NaCl, anisomycin and TNFα is shown. B. Histogram showing the percentage of p38 SAPK dependent (black bars) and independent (red bars) genes. We have considered a gene is p38 SAPK dependent when its expression is reduced at least by 50% in two independent treatments. C, Binomial statistics showing that transcription factor activity is the most significant GO molecular function enriched among the 30 common genes. The five common up-regulated transcription factors are shown.
Ferreiro et al. BMC Genomics 2010 11:144 doi:10.1186/1471-2164-11-144