BMC Genomics

official impact factor 4.21
Search for
Advanced search
BMC Genomics
Tools
Share this article
Open Access Research article

Sex-dimorphic gene expression and ineffective dosage compensation of Z-linked genes in gastrulating chicken embryos

Shaobing O Zhang1,2, Sachin Mathur1,3, Gaye Hattem1, Olivier Tassy1,2,5 and Olivier Pourquié1,2,4,6*

Author Affiliations

1 Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, MO 64110, USA

2 Howard Hughes Medical Institute, Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, MO 64110, USA

3 University of Missouri-Kansas City, School of Computing and Engineering, 5100 Rockhill Road, Kansas City, MO 64110 USA

4 Department of Anatomy & Cell Biology, The University of Kansas School of Medicine, Kansas City, KS 66103 USA

5 IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Illkirch, F-67400 France; Inserm, U.964, Illkirch, F-67400 France

6 IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Illkirch, F-67400 France; Inserm, U.964, Illkirch, F-67400 France; CNRS, UMR7104, Illkirch, F-67400 France; Université de Strasbourg, Strasbourg, F-67000 France

For all author emails, please log on.

BMC Genomics 2010, 11:13 doi:10.1186/1471-2164-11-13

Published: 7 January 2010

Additional files

Additional file 1:

List of the probesets that are expressed significantly higher in males than in females. The cutoff is set at 5% FDR.

Format: XLS Size: 251KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

List of the probesets that are regarded as male-biased. The cutoff is set at M:F ratio of 1.5.

Format: XLS Size: 180KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

List of the probesets that are expressed significantly higher in females than in males. The cutoff is set at 5% FDR.

Format: XLS Size: 36KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 4:

List of the probesets that are regarded as female-biased. The cutoff is set at F:M ratio of 1.5.

Format: XLS Size: 30KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 5:

List of all the 689 chrZ probesets that are expressed in day-1 embryos. The M:F ratios of these probesets are calculated.

Format: XLS Size: 338KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 6:

List of the probesets that are regarded as compensated. The criteria is M:F ratio value in the range of 0.8-1.3.

Format: XLS Size: 124KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 7:

List of the probesets that are regarded as non-compensated. The criteria is M:F ratio value greater than 1.5.

Format: XLS Size: 162KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 8:

Amplitude map of Z chromosome gene expression. The running averages of absolute values of log2 (M:F) are plotted along Z chromosome position.

Format: JPEG Size: 266KB Download file

Open Data

Additional file 9:

List of mouse genes with orthologs in the list of chicken non-compensated Z genes. These genes are involved in mouse male reproductive traits as indicated by GO analysis.

Format: XLS Size: 20KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data