Figure 1.

Effects of synonymous codon substitutions on %MinMax. The %MinMax calculation was applied to a series of synonymous sequences encoding the N-terminal 18 amino acids of Salmonella phage P22 tailspike. The first 18 codons of the wild type tailspike mRNA sequence (middle line) can be changed to common codons (bold text) or rare codons (gray text), resulting in dramatic differences in the %MinMax output, without altering the underlying amino acid sequence.

Clarke and Clark BMC Genomics 2010 11:118   doi:10.1186/1471-2164-11-118
Download authors' original image