Table 1

Analysis of communication pathways for Long Term Hematopoietic Stem Cells (LT-HSC)

Gene expressed in LT-HSC

Mean Intensity

Corresponding gene in stroma

Mean Intensity

NIH3T3

Osteoblasts


activin receptor IIB

267

bone morphogenetic protein 4

1335

66

252

bone morphogenetic protein 4

169

bone morphogenetic protein receptor, type 1A

497

274

384

chemokine (C-X-C motif) receptor 4

372

chemokine (C-X-C motif) ligand 12

12222

23

798

epidermal growth factor receptor

149

epiregulin

422

288

153

insulin-like growth factor 2

105

insulin-like growth factor 2 receptor

535

1772

1704

Integrin alpha 4

1675

junction adhesion molecule 2

201

16

26

integrin beta 1 (fibronectin receptor beta)

307

junction adhesion molecule 2

201

16

26

integrin beta 2

558

junction adhesion molecule 3

152

42

204

jagged 2

222

Notch gene homolog 3 (Drosophila)

367

161

48

oncostatin M

115

oncostatin M receptor

1151

1349

131

epidermal growth factor receptor

149

transforming growth factor alpha

261

13

21

Integrin alpha 4

1675

vascular cell adhesion molecule 1

692

182

929

integrin beta 1 (fibronectin receptor beta)

307

vascular cell adhesion molecule 1

692

182

929

integrin beta 7

329

vascular cell adhesion molecule 1

692

182

929

kinase insert domain protein receptor

311

vascular endothelial growth factor A

179

1006

169


Zetterblad et al. BMC Genomics 2010 11:108   doi:10.1186/1471-2164-11-108

Open Data