Open Access Research article

Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication

Jenny Zetterblad2, Hong Qian2, Sasan Zandi2, Robert Månsson1, Anna Lagergren1, Frida Hansson1, David Bryder3, Nils Paulsson1 and Mikael Sigvardsson12*

Author Affiliations

1 Department for Hematopoietic Stemcell Biology, Lund Stem Cell Center, BMC B12, 221 84 Lund, Sweden

2 Institution for Clinical and Experimental Science, Linköping Universitet, 581 85 Linköping, Sweden

3 Department for Immunology, Lund University, BMC D14, 221 84 Lund, Sweden

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BMC Genomics 2010, 11:108  doi:10.1186/1471-2164-11-108

Published: 12 February 2010

Additional files

Additional file 1:

Data base information. Excel sheet with information about all receptor ligand pairs investigated in this report.

Format: XLS Size: 2.3MB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 2:

Receptor ligand interactions between stroma cells and hematopoetic stem cells. A table with the full information about receptor ligand pairs that may be involved in the communication between stroma and hematopoetic stem cells (HSC).

Format: XLS Size: 41KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

Receptor ligand interactions between stroma cells and multipotent progenitor cells. A table with the full information about receptor ligand pairs that may be involved in the communication between stroma and multipotent progenitors (MPP).

Format: XLS Size: 33KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 4:

Receptor ligand interactions between stroma cells and lymphoid primed multipotent progenitors. A table with the full information about receptor ligand pairs that may be involved in the communication between stroma and lymphoid primed multipotent progenitors (LMPP).

Format: XLS Size: 40KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 5:

Receptor ligand interactions between stroma cells and common lymphoid progenitors. A table with the full information about receptor ligand pairs that may be involved in the communication between stroma and common lymhpoid progenitors (CLP).

Format: XLS Size: 49KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 6:

Receptor ligand interactions between stroma cells and granulocyte monocyte progenitors. A table with the full information about receptor ligand pairs that may be involved in the communication between stroma and granulocyte monocyte progenitors (GMP).

Format: XLS Size: 37KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 7:

Receptor ligand interactions between stroma cells and pro-B cells. A table with the full information about receptor ligand pairs that may be involved in the communication between stroma and pro-B cells.

Format: XLS Size: 42KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 8:

Receptor ligand interactions between stroma cells and pre-B cells. A table with the full information about receptor ligand pairs that may be involved in the communication between stroma and pre-B cells.

Format: XLS Size: 36KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 9:

Receptor ligand interactions between stroma cells and B cells. A table with the full information about receptor ligand pairs that may be involved in the communication between stroma and B cells.

Format: XLS Size: 38KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data