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Open Access Research article

U12 type introns were lost at multiple occasions during evolution

Sebastian Bartschat12 and Tore Samuelsson1*

Author Affiliations

1 Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Box 440, SE-405 30 Göteborg, Sweden

2 Bioinformatics Group, Department of Computer Science and Interdisciplinary Center for Bioinformatics, University of Leipzig, Haertelstrasse 16-18, D-04107 Leipzig, Germany

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BMC Genomics 2010, 11:106  doi:10.1186/1471-2164-11-106

Published: 11 February 2010

Additional files

Additional file 1:

Intron length statistics. Upper panel: Distribution of lengths in the size range 1-300 nt for all introns (U2 and U12) of T. spiralis, E. histolytica, A. castellanii, P. tricornutum, M. brevicollis, and C. reinhardtii. Lower panel: Mean intron lengths for all species with U12 introns considered in this work.

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Open Data

Additional file 2:

Sequences of introns. Sequences of introns referred to in Tables 1 and 2. Sequences of R. oryzae ribosomal protein S13 genes and introns.

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Open Data