Figure 9.

Mapping of pTTSs and miRNA included into IGF2 gene region. A: Mapping on primary miRNA (hsa-mir-483) and pTFO on the evolutionally conserve intronic region of IGF2 gene. B: secondary structure of primary miRNA (hsa-mir-483). Pink color of nucleotide symbol: mature siRNA, blue color of nucleotide symbol: polypurine sequence, red color of nucleotide symbol: polypyrimidine sequence located on the some strand as double helix DNA. One substitution on Y in the R starch is allowed. C: pTTS (TTS15011002112005) includes binding site (TTCCCCTCTCCC) of transcription factor MZF1.

Jenjaroenpun and Kuznetsov BMC Genomics 2009 10(Suppl 3):S9   doi:10.1186/1471-2164-10-S3-S9