Additional file 2.
Electrostatic surface potential of PvPGIP2 with a single mutation at 224. Q(224) of PvPGIP2 is mutated to K which is the residue found in PvPGIP1. The electrostatic surface potential changes considerably with a single mutation when compared to Figure 5B. Experimental studies on this single mutation have shown a 70% reduction in the inhibition ability of PvPGIP2.
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Maulik et al. BMC Genomics 2009 10(Suppl 3):S19 doi:10.1186/1471-2164-10-S3-S19