Table 2

Parameters for simulating the seven artificial datasets.

Sample (in ascending order of age)

Dataset

Pattern

1-10

11-20

21-30

31-40

41-50

51-60

61-70

71-80


DE, 2

C

4, 2

4, 2

4, 2

4, 2

4, 2

4, 2

4, 2

4, 2

L

1, 2

2, 2

3, 2

4, 2

5, 2

6, 2

7, 2

8, 2

NL

1, 2

2, 2

3, 2

4, 2

5, 2

4, 2

3, 2

1, 2


DE, 5

C

4, 5

4, 5

4, 5

4, 5

4, 5

4, 5

4, 5

4, 5

L

1, 5

2, 5

3, 5

4, 5

5, 5

6, 5

7, 5

8, 5

NL

1, 5

2, 5

3, 5

4, 5

5, 5

4, 5

3, 5

1, 5


DE, 5+outliers

C

4, 5

4, 5

4, 5

4, 5

4, 5

4, 5

4, 5

4, 5

L

1, 5

2, 5

3, 5

4, 5

5, 5

6, 5

7, 5

8, 5

NL

1, 5

2, 5

3, 5

4, 5

5, 5

4, 5

3, 5

1, 5


DE, 9

C

4, 9

4, 9

4, 9

4, 9

4, 9

4, 9

4, 9

4, 9

L

1, 9

2, 9

3, 9

4, 9

5, 9

6, 9

7, 9

8, 9

NL

1, 9

2, 9

3, 9

4, 9

5, 9

4, 9

3, 9

1, 9


DE, 9+outliers

C

4, 9

4, 9

4, 9

4, 9

4, 9

4, 9

4, 9

4, 9

L

1, 9

2, 9

3, 9

4, 9

5, 9

6, 9

7, 9

8, 9

NL

1, 9

2, 9

3, 9

4, 9

5, 9

4, 9

3, 9

1, 9


DV

C

4, 3

4, 3

4, 3

4, 3

4, 3

4, 3

4, 3

4, 3

L

4, 1

4, 2

4, 3

4, 4

4, 5

4, 6

4, 7

4, 8

NL

4, 1

4, 2

4, 3

4, 4

4, 5

4, 3

4, 2

4, 1


DV+outliers

C

4, 3

4, 3

4, 3

4, 3

4, 3

4, 3

4, 3

4, 3

L

4, 1

4, 2

4, 3

4, 4

4, 5

4, 6

4, 7

4, 8

NL

4, 1

4, 2

4, 3

4, 4

4, 5

4, 3

4, 2

4, 1


Gene expression values can be simulated by drawing values from a normal distribution with mean μ and standard deviation σ. The choice of μ and σ depends on the age group of a sample and the type of pattern each gene is simulating. The complete list of μ and σ used to simulate the seven artificial microarray datasets are shown here, given as μ, σ pairs.

Ho et al. BMC Genomics 2009 10(Suppl 3):S16   doi:10.1186/1471-2164-10-S3-S16

Open Data