Fumarate/nitrate response regulator network in P. multocida in response to enrofloxacin visualized in Pathway Studio. P. multocida sub-MIC ENR response was marked by significant changes in fnr response regulated genes. Red nodes are genes with increased expression and green nodes are genes with decreased expression. The rest of the interacting nodes are shown in gray. These nodes had no significant changes in expression or were orthologs from additional gram-negative species in the molecular interaction database in Pathway Studio.
Nanduri et al. BMC Genomics 2009 10(Suppl 2):S4 doi:10.1186/1471-2164-10-S2-S4