This article is part of the supplement: The 2008 International Conference on Bioinformatics & Computational Biology (BIOCOMP'08)

Open Access Highly Accessed Introduction

High-throughput next-generation sequencing technologies foster new cutting-edge computing techniques in bioinformatics

Mary Qu Yang1, Brian D Athey2, Hamid R Arabnia3, Andrew H Sung4, Qingzhong Liu4, Jack Y Yang5, Jinghe Mao6 and Youping Deng7*

Author affiliations

1 National Human Genome Research Institute, National Institutes of Health (NIH), U.S. Department of Health and Human Services, Bethesda, MD 20892, USA

2 National Center for Integrated Biomedical Informatics (NCIBI) and Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA

3 Department of Computer Science, University of Georgia, Athens, GA 30602-7404, USA

4 Department of Computer Science, New Mexico Tech, Socorro, NM 87801, USA

5 Harvard University, P.O. Box 400888, Cambridge, MA 02140-0888, USA

6 Department of Biology, Tougaloo College, Tougaloo, MS 39174, USA

7 Department of Biological Sciences, University of Southern Mississippi, Hattiesburg, MS 39406, USA

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Citation and License

BMC Genomics 2009, 10(Suppl 1):I1  doi:10.1186/1471-2164-10-S1-I1

Published: 7 July 2009


The advent of high-throughput next generation sequencing technologies have fostered enormous potential applications of supercomputing techniques in genome sequencing, epi-genetics, metagenomics, personalized medicine, discovery of non-coding RNAs and protein-binding sites. To this end, the 2008 International Conference on Bioinformatics and Computational Biology (Biocomp) – 2008 World Congress on Computer Science, Computer Engineering and Applied Computing (Worldcomp) was designed to promote synergistic inter/multidisciplinary research and education in response to the current research trends and advances. The conference attracted more than two thousand scientists, medical doctors, engineers, professors and students gathered at Las Vegas, Nevada, USA during July 14–17 and received great success. Supported by International Society of Intelligent Biological Medicine (ISIBM), International Journal of Computational Biology and Drug Design (IJCBDD), International Journal of Functional Informatics and Personalized Medicine (IJFIPM) and the leading research laboratories from Harvard, M.I.T., Purdue, UIUC, UCLA, Georgia Tech, UT Austin, U. of Minnesota, U. of Iowa etc, the conference received thousands of research papers. Each submitted paper was reviewed by at least three reviewers and accepted papers were required to satisfy reviewers' comments. Finally, the review board and the committee decided to select only 19 high-quality research papers for inclusion in this supplement to BMC Genomics based on the peer reviews only. The conference committee was very grateful for the Plenary Keynote Lectures given by: Dr. Brian D. Athey (University of Michigan Medical School), Dr. Vladimir N. Uversky (Indiana University School of Medicine), Dr. David A. Patterson (Member of United States National Academy of Sciences and National Academy of Engineering, University of California at Berkeley) and Anousheh Ansari (Prodea Systems, Space Ambassador). The theme of the conference to promote synergistic research and education has been achieved successfully.