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Open Access Highly Accessed Research article

Global gene expression analysis reveals reduced abundance of putative microRNA targets in human prostate tumours

Ruping Sun, Xuping Fu, Yao Li*, Yi Xie and Yumin Mao*

Author Affiliations

State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, PR China

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BMC Genomics 2009, 10:93  doi:10.1186/1471-2164-10-93

Published: 26 February 2009

Additional files

Additional file 1:

Supplementary Table 1. Comparison of miRNA target expression between in cancers and in normal tissues. The complete dataset of comparing the expression levels of miRNA targets between in cancers and in normal tissues.

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Additional file 2:

Supplementary Table 2. A weak negative correlation between the differential expression scores of individual miRNAs and the RR values of their targets. The differential expression scores of individual miRNAs and the RR values of their targets.

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Additional file 3:

Supplementary Table 3. Correlation analysis between the transcript levels of individual miRNAs and those of their putative targets using a dataset containing the expression values of both miRNAs and mRNAs in ten prostate tumours and ten corresponding surrounding non-tumour tissues. The average Pearson correlation coefficients for individual miRNAs with either target mRNAs or all mRNAs.

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Open Data