Figure 2.

The relative abundance and diversity of each Echis genus venom toxin family. a) Relative expression levels of non-singleton clusters of the most representative venom toxin families and b) Relative expression levels of total non-singleton clusters and singletons representing the less numerically represented venom toxin families (Others) are expressed as a percentage of total toxin encoding transcripts. Column to the right indicates the proportion of invertebrate prey consumed and the corresponding correlation of venom toxicity to scorpions: ++, high; +, moderate; -, low [adapted from [10]]. Key - PI-PIV: sub-classes of snake venom metalloproteinases (SVMP); DIS: short coding disintegrins; CTL: C-type lectins; PLA2: group II phospholipases A₂; SP: serine proteases; LAO: L-amino oxidases; CRISP: cysteine-rich secretory proteins; VEGF: vascular endothelial growth factors; NGF: nerve growth factors; PEPT: peptidases - aminopeptidase, dipeptidyl peptidase III and neprilysin; PE: Purine liberators - phosphdiesterase, 5'-nucleotidase and ectonucleoside triphosphate diphosphohydrolase (E-NTPase); HYAL: hyaluronidases; LAL: lysosomal acid lipases; RLAP: renin-like aspartic proteases; KTZ: kunitz-type protease inhibitors.