Table 1 |
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|
List of the genes up-regulated by enteric glial cells in intestinal epithelial cells. |
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|
Gene Symbol |
Genbank |
Description |
% up-regulation (/control) |
Fold difference |
|
|
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|
TXNIP |
thioredoxin interacting protein |
217,60 |
3,18 |
|
|
ANKRD1 |
ankyrin repeat domain 1 (cardiac muscle) |
169,22 |
2,69 |
|
|
FN1 |
fibronectin 1 |
152,16 |
2,52 |
|
|
TUBB3 |
tubulin, beta 3 |
149,94 |
2,50 |
|
|
MGLL |
monoglyceride lipase |
135,97 |
2,36 |
|
|
METTL7A |
methyltransferase like 7A |
132,96 |
2,33 |
|
|
PKN2 |
protein kinase N2 |
128,33 |
2,28 |
|
|
/ |
synonyms: KIAA0056, MGC104671; Homo sapiens KIAA0056 protein (hCAP-D3), mRNA. |
115,09 |
2,15 |
|
|
EPB41L2 |
erythrocyte membrane protein band 4.1-like 2 |
110,50 |
2,11 |
|
|
AASS |
aminoadipate-semialdehyde synthase |
110,15 |
2,10 |
|
|
ACTG2 |
actin, gamma 2, smooth muscle, enteric |
102,56 |
2,03 |
|
|
B4GALT5 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
102,38 |
2,02 |
|
|
SNX2 |
sorting nexin 2 |
102,38 |
2,02 |
|
|
VIP |
vasoactive intestinal peptide |
102,33 |
2,02 |
|
|
EIF4A2 |
eukaryotic translation initiation factor 4A, isoform 2 |
102,14 |
2,02 |
|
|
/ |
RNA-binding protein |
101,66 |
2,02 |
|
|
POLR3F |
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa |
94,46 |
1,94 |
|
|
PNRC1 |
proline-rich nuclear receptor coactivator 1 |
93,24 |
1,93 |
|
|
NPPB |
natriuretic peptide precursor B |
83,97 |
1,84 |
|
|
/ |
Homo sapiens cDNA clone IMAGE:4690793, with apparent retained intron. |
82,20 |
1,82 |
|
|
KRT8 |
keratin 8 |
81,96 |
1,82 |
|
|
SAT1 |
spermidine/spermine N1-acetyltransferase 1 |
80,24 |
1,80 |
|
|
ASS1 |
argininosuccinate synthetase 1 |
76,73 |
1,77 |
|
|
S100A11P |
/ |
75,22 |
1,75 |
|
|
SLC7A7 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 |
72,31 |
1,72 |
|
|
HAGH |
hydroxyacylglutathione hydrolase |
69,54 |
1,70 |
|
|
BNIP3L |
BCL2/adenovirus E1B 19 kDa interacting protein 3-like |
69,19 |
1,69 |
|
|
/ |
PRR5-ARHGAP8 fusion |
68,01 |
1,68 |
|
|
BNIP3 |
BCL2/adenovirus E1B 19 kDa interacting protein 3 |
67,84 |
1,68 |
|
|
IL18 |
interleukin 18 (interferon-gamma-inducing factor) |
67,14 |
1,67 |
|
|
RDM1 |
RAD52 motif 1 |
67,11 |
1,67 |
|
|
FAM107B |
family with sequence similarity 107, member B |
65,70 |
1,66 |
|
|
PLAC8 |
placenta-specific 8 |
63,77 |
1,64 |
|
|
SMARCA1 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
63,72 |
1,64 |
|
|
PLOD2 |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
62,87 |
1,63 |
|
|
TMSB4Y |
thymosin, beta 4, Y-linked |
62,77 |
1,63 |
|
|
SCPEP1 |
serine carboxypeptidase 1 |
60,96 |
1,61 |
|
|
LAMA5 |
laminin, alpha 5 |
60,53 |
1,61 |
|
|
LAMC1 |
laminin, gamma 1 (formerly LAMB2) |
59,89 |
1,60 |
|
|
METAP1 |
methionyl aminopeptidase 1 |
59,55 |
1,60 |
|
|
IQGAP2 |
IQ motif containing GTPase activating protein 2 |
58,98 |
1,59 |
|
|
C1orf43 |
chromosome 1 open reading frame 43 |
56,86 |
1,57 |
|
|
CASP4 |
caspase 4, apoptosis-related cysteine peptidase |
55,71 |
1,56 |
|
|
BTG1 |
B-cell translocation gene 1, anti-proliferative |
54,63 |
1,55 |
|
|
SLC2A1 |
solute carrier family 2 (facilitated glucose transporter), member 1 |
54,34 |
1,54 |
|
|
DCTN2 |
dynactin 2 (p50) |
52,68 |
1,53 |
|
|
TOP2A |
topoisomerase (DNA) II alpha 170 kDa |
52,42 |
1,52 |
|
|
KRT18 |
keratin 18 |
51,16 |
1,51 |
|
|
LAMC1 |
laminin, gamma 1 (formerly LAMB2) |
50,37 |
1,50 |
|
|
PRC1 |
protein regulator of cytokinesis 1 |
50,13 |
1,50 |
|
|
IMPDH2 |
IMP (inosine monophosphate) dehydrogenase 2 |
49,46 |
1,49 |
|
|
/ |
LRP16 protein |
48,20 |
1,48 |
|
|
PLD3 |
phospholipase D family, member 3 |
46,99 |
1,47 |
|
|
RNF4 |
ring finger protein 4 |
44,88 |
1,45 |
|
|
/ |
Homo sapiens 3 BAC RP11-23J16 complete sequence. |
42,10 |
1,42 |
|
|
SMARCA1 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
41,18 |
1,41 |
|
|
DYNLT3 |
dynein, light chain, Tctex-type 3 |
40,06 |
1,40 |
|
|
PPARG |
peroxisome proliferative activated receptor, gamma |
38,92 |
1,39 |
|
|
GLRX |
glutaredoxin (thioltransferase) |
37,78 |
1,38 |
|
|
PTK2 |
PTK2 protein tyrosine kinase 2 |
37,72 |
1,38 |
|
|
CDH1 |
cadherin 1, type 1, E-cadherin (epithelial) |
36,87 |
1,37 |
|
|
RNASE4 |
ribonuclease, RNase A family, 4 |
31,40 |
1,31 |
|
|
CTSH |
cathepsin H |
29,45 |
1,29 |
|
|
MKI67 |
antigen identified by monoclonal antibody Ki-67 |
29,28 |
1,29 |
|
|
EIF2A |
eukaryotic translation initiation factor 2A, 65 kDa |
26,54 |
1,27 |
|
|
TGFBI |
transforming growth factor, beta-induced, 68 kDa |
25,95 |
1,26 |
|
|
MLLT3 |
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
22,42 |
1,22 |
|
|
APOBEC3B |
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
22,20 |
1,22 |
|
|
ADD3 |
adducin 3 (gamma) |
20,82 |
1,21 |
|
|
FTH1 |
ferritin, heavy polypeptide 1 |
15,97 |
1,16 |
|
|
|
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|
Van Landeghem et al. BMC Genomics 2009 10:507 doi:10.1186/1471-2164-10-507 |
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