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Open Access Research article

Comprehensive analysis of the pseudogenes of glycolytic enzymes in vertebrates: the anomalously high number of GAPDH pseudogenes highlights a recent burst of retrotrans-positional activity

Yuen-Jong Liu12, Deyou Zheng3, Suganthi Balasubramanian2, Nicholas Carriero2, Ekta Khurana2, Rebecca Robilotto4 and Mark B Gerstein245*

Author Affiliations

1 Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis Street, Boston, MA, USA

2 Department of Molecular Biophysics and Biochemistry, P.O. Box 208114, Yale University, New Haven, CT 06520, USA

3 Albert Einstein College of Medicine of Yeshiva University, Department of Neurology, Rose F. Kennedy Center, 1410 Pelham Parkway South, Room 915B, Bronx, NY 10461, USA

4 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA

5 Department of Computer Science, Yale University, Bass 432, 266 Whitney Avenue, New Haven, CT 06520, USA

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BMC Genomics 2009, 10:480  doi:10.1186/1471-2164-10-480

Published: 16 October 2009

Additional files

Additional file 1:

Supplement. The sensitivity of our pseudogene pipeline is clarified and the sets of duplicated-processed pseudogenes are cataloged.

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