Table 1

Comparison of genes (or operons) showing differential expression in microarray analysis and previously determined to be CepIR regulated using transcriptional fusions.

Gene

Functiona

Change (fold) for K56-dI2 (cepI) vs K56-2

Change (fold) for K56-R2 (cepR) vs K56-2

Change (fold) for K56-2cciR vs K56-2

Change (fold) for K56-2cepRcciIR vs K56-2


Promoter fusionb

Microarrayc

Microarrayc

Microarrayc


BCAL0111

putative TPR domain

-3.7

-2.2

NC

-2.2

BCAL0380

ABC transporter ATP-binding subunit

-2.7

-2.3

NC

NC

BCAL0812

sigma 54 modulation protein

-2.0

-2.8

NC

NC

BCAL1814d

MerR family regulatory protein

2.2

-2.9

-2.7

NC

BCAL1990

glucose-6-phosphate isomerase Pgi

-2.2

-2.6

NC

NC

BCAL2244

urocanate hydratase HutU

-2.2

-2.1

NC

NC

BCAL2931d

radical SAM superfamily protein

3.2

2.0

NC

NC

BCAL3006d

cold shock-like protein CspA

-1.9

-5.6

2.8

-4.9

BCAS0221

ABC transporter ATP-binding protein AfcB (pseudogene)

-1.7

-3.6

2.9

NC

BCAS0409

zinc metalloprotease ZmpA

-2.6

-5.3

4.0

-4.5


aFunction derived from B. cenocepacia J2315 [34].

cChange in 16-h cultures of cepI mutant compared to 16-h cultures of K56-2 as determined by promoter fusion Subsin et al. 2007 [27].

cChange in 16-h cultures of cepR, cciR or cepRcciIR mutants compared to 16-h cultures of K56-2 as determined by microarray analysis with at least two biological replicates (NC, no change).

dPresence of a cep box motif was identified by Subsin et al. 2007 [27] for this gene.

O'Grady et al. BMC Genomics 2009 10:441   doi:10.1186/1471-2164-10-441

Open Data