Research article
Phase Coupled Meta-analysis: sensitive detection of oscillations in cell cycle gene expression, as applied to fission yeast
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* Corresponding authors: Saumyadipta Pyne saumyadipta_pyne@dfci.harvard.edu - Bruce Futcher bfutcher@ms.cc.sunysb.edu
1 Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA
2 Present address: Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
3 Department of Statistics, Harvard University, Cambridge, MA 02138, USA
4 Department of Biological Sciences, RCWD, Sookmyung Women's University, Seoul, Republic of Korea
5 Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794, USA
BMC Genomics 2009, 10:440 doi:10.1186/1471-2164-10-440
Published: 17 September 2009Additional files
Additional file 1:
PCM rank list of fission yeast genes. The spreadsheet provides the genome-wide rank of fission yeast genes due to Phase-Coupled Meta-analysis (PCM). It also shows whether a gene was reported by Oliva et al. or Marguerat et al. as periodic, its median phase over all experiments and its circular variance, and to which cluster due to Oliva et al. it belongs. The last field also indicates membership in the new Cribo cluster.
Format: XLS Size: 557KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 2:
Supplementary figures. Fig. S1 plots the distribution of cell cycle phases for genes from the PCM rank-list. Fig. S2 plots the genome-wide distribution of the circular variance of every gene's phases across experiments.
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This file can be viewed with: Adobe Acrobat Reader
Additional file 3:
High resolution plot. High resolution version of Fig. 7.
Format: TIFF Size: 1.5MB Download file
Additional file 4:
High resolution plot. High resolution version of Fig. 8.
Format: TIFF Size: 4.5MB Download file