Table 1

Top genes upregulated in CD16+ compared to CD16- Mo

CD16+ Mo AU


Gene Symbol

CD16+/CD16- Ratio

p-value

Mean

SD

GeneTitle


FCGR3A

20,1

0,000

36975

6660

Fc fragment of IgG, low affinity IIIa, receptor for (CD16)

CDKN1C

18,4

0,000

23838

5132

cyclin-dependent kinase inhibitor 1C (p57, Kip2)

MTSS1

5,7

0,000

12285

2678

metastasis suppressor 1

SIGLEC10

4,8

0,000

10657

3068

sialic acid binding Ig-like lectin 10

IFITM1

4,5

0,026

13823

10613

interferon induced transmembrane protein 1 (9–27)

HMOX1

3,5

0,000

16791

4339

heme oxygenase (decycling) 1

TAGLN

3,2

0,000

11950

3480

Transgelin

TCF7L2

3,0

0,000

16772

4608

transcription factor 7-like 2 (T-cell specific, HMG-box)

MS4A7

2,8

0,000

22645

6376

membrane-spanning 4-domains, subfamily A, member 7

CSF1R

2,8

0,000

22838

6537

colony stimulating factor 1 receptor

NAP1L1

2,8

0,000

34370

5546

nucleosome assembly protein 1-like 1

IFITM2

2,5

0,000

58835

17536

interferon induced transmembrane protein 2 (1-8D)

SOD1

2,5

0,000

11300

2491

superoxide dismutase 1

IFITM3

2,5

0,022

40793

15947

interferon induced transmembrane protein 3 (1-8U)

LST1

2,5

0,000

42904

13661

leukocyte specific transcript 1

CX3CR1

2,4

0,041

25882

11806

chemokine (C-X3-C motif) receptor 1

LILRB1

2,4

0,000

15534

4951

leukocyte immunoglobulin-like receptor, subfamily B, member 1

PSCDBP

2,3

0,000

12459

2539

pleckstrin homology, Sec7 and coiled-coil domains, binding protein

ITGAL

2,3

0,000

13269

3384

integrin, alpha L (antigen CD11A)

C6orf187

2,3

0,022

14752

5263

chromosome 6 open reading frame 187

KLF2

2,3

0,000

23783

7614

Kruppel-like factor 2 (lung)

WARS

2,3

0,000

18466

5567

tryptophanyl-tRNA synthetase

MAFB

2,3

0,000

16707

5853

v-maf musculoaponeurotic fibrosarcoma oncogene homolog B

GCH1

2,2

0,022

10956

3586

GTP cyclohydrolase 1 (dopa-responsive dystonia)

CD97

2,2

0,000

10566

3203

CD97 antigen

CTSC

2,2

0,000

10079

2619

cathepsin C

PIK3AP1

2,1

0,000

16825

4941

phosphoinositide-3-kinase adaptor protein 1

MAIL

2,1

0,000

15859

4883

molecule possessing ankyrin repeats induced by lipopolysaccharide

LYN

2,1

0,000

19388

3520

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

BCL2A1

2,1

0,022

11110

5056

BCL2-related protein A1

PECAM1

2,0

0,000

22679

7106

platelet/endothelial cell adhesion molecule (CD31 antigen)


Shown are differentially expressed genes (>2-fold higher in CD16+ compared to CD16- Mo) with the highest expression levels (>10,000 AU). AU, arbitrary units.

Ancuta et al. BMC Genomics 2009 10:403   doi:10.1186/1471-2164-10-403

Open Data