Table 1 |
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Top genes upregulated in CD16+ compared to CD16- Mo |
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CD16+ Mo AU |
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|
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|
Gene Symbol |
CD16+/CD16- Ratio |
p-value |
Mean |
SD |
GeneTitle |
|
|
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|
FCGR3A |
20,1 |
0,000 |
36975 |
6660 |
Fc fragment of IgG, low affinity IIIa, receptor for (CD16) |
|
CDKN1C |
18,4 |
0,000 |
23838 |
5132 |
cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
|
MTSS1 |
5,7 |
0,000 |
12285 |
2678 |
metastasis suppressor 1 |
|
SIGLEC10 |
4,8 |
0,000 |
10657 |
3068 |
sialic acid binding Ig-like lectin 10 |
|
IFITM1 |
4,5 |
0,026 |
13823 |
10613 |
interferon induced transmembrane protein 1 (9–27) |
|
HMOX1 |
3,5 |
0,000 |
16791 |
4339 |
heme oxygenase (decycling) 1 |
|
TAGLN |
3,2 |
0,000 |
11950 |
3480 |
Transgelin |
|
TCF7L2 |
3,0 |
0,000 |
16772 |
4608 |
transcription factor 7-like 2 (T-cell specific, HMG-box) |
|
MS4A7 |
2,8 |
0,000 |
22645 |
6376 |
membrane-spanning 4-domains, subfamily A, member 7 |
|
CSF1R |
2,8 |
0,000 |
22838 |
6537 |
colony stimulating factor 1 receptor |
|
NAP1L1 |
2,8 |
0,000 |
34370 |
5546 |
nucleosome assembly protein 1-like 1 |
|
IFITM2 |
2,5 |
0,000 |
58835 |
17536 |
interferon induced transmembrane protein 2 (1-8D) |
|
SOD1 |
2,5 |
0,000 |
11300 |
2491 |
superoxide dismutase 1 |
|
IFITM3 |
2,5 |
0,022 |
40793 |
15947 |
interferon induced transmembrane protein 3 (1-8U) |
|
LST1 |
2,5 |
0,000 |
42904 |
13661 |
leukocyte specific transcript 1 |
|
CX3CR1 |
2,4 |
0,041 |
25882 |
11806 |
chemokine (C-X3-C motif) receptor 1 |
|
LILRB1 |
2,4 |
0,000 |
15534 |
4951 |
leukocyte immunoglobulin-like receptor, subfamily B, member 1 |
|
PSCDBP |
2,3 |
0,000 |
12459 |
2539 |
pleckstrin homology, Sec7 and coiled-coil domains, binding protein |
|
ITGAL |
2,3 |
0,000 |
13269 |
3384 |
integrin, alpha L (antigen CD11A) |
|
C6orf187 |
2,3 |
0,022 |
14752 |
5263 |
chromosome 6 open reading frame 187 |
|
KLF2 |
2,3 |
0,000 |
23783 |
7614 |
Kruppel-like factor 2 (lung) |
|
WARS |
2,3 |
0,000 |
18466 |
5567 |
tryptophanyl-tRNA synthetase |
|
MAFB |
2,3 |
0,000 |
16707 |
5853 |
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B |
|
GCH1 |
2,2 |
0,022 |
10956 |
3586 |
GTP cyclohydrolase 1 (dopa-responsive dystonia) |
|
CD97 |
2,2 |
0,000 |
10566 |
3203 |
CD97 antigen |
|
CTSC |
2,2 |
0,000 |
10079 |
2619 |
cathepsin C |
|
PIK3AP1 |
2,1 |
0,000 |
16825 |
4941 |
phosphoinositide-3-kinase adaptor protein 1 |
|
|
2,1 |
0,000 |
15859 |
4883 |
molecule possessing ankyrin repeats induced by lipopolysaccharide |
|
LYN |
2,1 |
0,000 |
19388 |
3520 |
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
|
BCL2A1 |
2,1 |
0,022 |
11110 |
5056 |
BCL2-related protein A1 |
|
PECAM1 |
2,0 |
0,000 |
22679 |
7106 |
platelet/endothelial cell adhesion molecule (CD31 antigen) |
|
|
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Shown are differentially expressed genes (>2-fold higher in CD16+ compared to CD16- Mo) with the highest expression levels (>10,000 AU). AU, arbitrary units. |
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Ancuta et al. BMC Genomics 2009 10:403 doi:10.1186/1471-2164-10-403 |
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