Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets
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* Corresponding authors: Petronela Ancuta petronela.ancuta@umontreal.ca - Dana Gabuzda dana_gabuzda@dfci.harvard.edu
BMC Genomics 2009, 10:403 doi:10.1186/1471-2164-10-403
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BioMed Central: 3 citations
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Research
Yoshimi Enose-Akahata, Eiji Matsuura, Yuetsu Tanaka, Unsong Oh, Steven Jacobson Retrovirology 2012, 9:16 (15 February 2012) This study shows that Minocycline significantly inhibited spontaneous lymphoproliferation and degranulation/IFN-gamma expression in CD8+ T cells of HAM/TSP patients. Treatment of minocycline also inhibited IFN-gamma expression in CD8+ T cells of HAM/TSP patients after Tax11-19 stimulation and downregulated MHC class I expression in CD14+ cells. The findings may be useful for future HAM/TSP therapy.
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Review
Host hindrance to HIV-1 replication in monocytes and macrophages Anna Bergamaschi, Gianfranco Pancino Retrovirology 2010, 7:31 (7 April 2010) |
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Minireview
The transcriptome of human monocyte subsets begins to emerge Fernando O Martinez Journal of Biology 2009, 8:99 (23 December 2009) Monocytes are circulating cells that can differentiate into macrophages with either repair and maintenance or inflammatory properties. Martinez discusses recent papers, including one published in BMC Genomics, that help define these distinct properties and thus identify therapeutic targets.
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