Table 6

ChIP-Seq simulations of depth of sequencing for S. cerevisiae

Fold Enrichment

10×

50×


Number of Reads

2,500,000

260,000

90,000

18,000


Number of reads required in order to identify greater than 95% of 600 simulated binding sites distributed evenly over the 12 Mb S. cerevisiae genome with average fold enrichments of 2×, 5×, 10× and 50×. See Methods for details of the simulation.

Lefrançois et al. BMC Genomics 2009 10:37   doi:10.1186/1471-2164-10-37

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