Open Access Highly Accessed Research article

Gene copy number variation throughout the Plasmodium falciparum genome

Ian H Cheeseman12*, Natalia Gomez-Escobar2, Celine K Carret3, Alasdair Ivens3, Lindsay B Stewart1, Kevin KA Tetteh1 and David J Conway12

Author Affiliations

1 Department of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK

2 Medical Research Council Laboratories, Fajara, PO Box 273, Banjul, The Gambia

3 Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK

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BMC Genomics 2009, 10:353  doi:10.1186/1471-2164-10-353

Published: 4 August 2009

Additional files

Additional file 1:

Supplementary Table 1. A summary of the chromosome, size and product of all CNV genes detected.

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Additional file 2:

Supplementary Figure 1. Amplified and deleted genes across all 16 isolates.

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Additional file 3:

Supplementary Table 2. A summary of the validated deletions in the Dd2 and Hb3 genome sequences.

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Additional file 4:

Supplementary Figure 2. Nucleotide diversity in non-variable, amplified and deleted genes.

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Additional file 5:

Supplementary Figure 3. AT tract density in CNV and non-CNV genes.

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Additional file 6:

Supplementary Figure 4. Correlation between hybridisation signal and SNPs in Hb3 and Dd2.

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Additional file 7:

Supplementary figure legends. Supplementary figure legends for supplementary figures 1-4.

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