Relationship between SNP frequencies estimated from sequencing of individual DNA templates and sequencing of pooled templates. R2 = 0.61, P < 0.001. False positives are arrayed along the x axis (y = 0) and false negatives are arrayed along the y axis (x = 0).
Wilding et al. BMC Genomics 2009 10:320 doi:10.1186/1471-2164-10-320