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Open Access Research article

Gene expression patterns in heterozygous Plk4 murine embryonic fibroblasts

Alan Morettin, Alejandra Ward, Jordan Nantais and John W Hudson*

Author Affiliations

Department of Biological Sciences, University of Windsor, Windsor, Ontario, Canada

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BMC Genomics 2009, 10:319  doi:10.1186/1471-2164-10-319

Published: 16 July 2009

Additional files

Additional file 1:

Supplementary Figure 1. Figure showing the results from the X-gal assay in plk4 wild type and heterozygous MEFs. Differences in senescence were determined at passages 3–5 for heterozygous and wild-type Plk4 MEFs by β-galactosidase assay. Senescing Human foreskin fibroblast (HFF-1) (passage 52) were used as a positive control. Arrows point to the characteristic blue perinuclear staining.

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