Table 4 |
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|
Mouse immune genes up-regulated in regressing GI-101A tumors at day 42 (F test p2-value < 0.001) |
|||||||
|
Gene LLID # |
Symbol |
Name |
HT-29 Control |
HT-29 GLV-1h68 |
GI-101A Control |
GI-101A GLV-1h68 |
GI-101A GLV-1h68 (day 21) |
|
|
|||||||
|
|
|||||||
|
Interleukins |
|||||||
|
|
|||||||
|
16068 |
Il18bp |
interleukin 18 binding protein |
1.31 |
2.18 |
1.00 |
13.28 |
5.70 |
|
|
|||||||
|
16173 |
Il18 |
interleukin 18 |
1.12 |
1.40 |
1.00 |
10.89 |
4.10 |
|
|
|||||||
|
16168 |
Il15 |
interleukin 15 |
1.02 |
1.51 |
1.00 |
5.20 |
2.86 |
|
|
|||||||
|
16154 |
Il10ra |
interleukin 10 receptor alpha |
0.74 |
0.90 |
1.00 |
3.51 |
2.08 |
|
|
|||||||
|
|
|||||||
|
Chemokines |
|||||||
|
|
|||||||
|
Cxcl11 |
Cxcl11/I-TAC |
0.92 |
1.75 |
1.00 |
13.57 |
5.69 |
|
|
|
|||||||
|
17329 |
Cxcl9 |
Cxcl9/Mig |
1.01 |
1.07 |
1.00 |
11.74 |
3.80 |
|
|
|||||||
|
20304 |
Ccl5 |
Ccl5/RANTES |
1.00 |
2.69 |
1.00 |
13.33 |
3.23 |
|
|
|||||||
|
20308 |
Ccl9 |
Ccl9/MRP-2/CCF18/MIP-1g |
1.56 |
3.14 |
1.00 |
12.03 |
6.60 |
|
|
|||||||
|
20304 |
Ccl5 |
Ccl5/RANTES |
1.11 |
2.57 |
1.00 |
9.81 |
2.56 |
|
|
|||||||
|
20306 |
Ccl7 |
Ccl7/MARC |
0.84 |
1.18 |
1.00 |
5.86 |
4.71 |
|
|
|||||||
|
20315 |
Cxcl12 |
Cxcl12/SDF-1/PBSF |
0.41 |
0.58 |
1.00 |
5.23 |
3.07 |
|
|
|||||||
|
20301 |
Ccl27 |
Ccl27/ALP/CTACK/ILC/Eskine |
1.86 |
1.91 |
1.00 |
5.17 |
1.66 |
|
|
|||||||
|
20308 |
Ccl9 |
Ccl9/MRP-2/CCF18/MIP-1g |
1.26 |
1.42 |
1.00 |
4.04 |
3.12 |
|
|
|||||||
|
|
|||||||
|
ISGs |
|||||||
|
|
|||||||
|
16145 |
Igtp |
interferon gamma induced GTPase |
1.15 |
3.31 |
1.00 |
48.21 |
10.11 |
|
|
|||||||
|
76933 |
Ifi27 |
interferon, alpha-inducible protein 27 |
0.76 |
0.91 |
1.00 |
12.84 |
10.04 |
|
|
|||||||
|
Ifi47 |
interferon gamma inducible protein 47 |
0.66 |
0.94 |
1.00 |
11.09 |
4.56 |
|
|
|
|||||||
|
Iigp2 |
interferon inducible GTPase 2 |
0.64 |
1.41 |
1.00 |
10.05 |
5.25 |
|
|
|
|||||||
|
16145 |
Igtp |
interferon gamma induced GTPase |
0.70 |
1.28 |
1.00 |
9.70 |
5.62 |
|
|
|||||||
|
17857 |
Mx1 |
myxovirus (influenza virus) resistance 1 |
0.62 |
1.46 |
1.00 |
9.46 |
6.41 |
|
|
|||||||
|
Ifi204 |
interferon activated gene 204 |
0.86 |
1.77 |
1.00 |
8.94 |
5.44 |
|
|
|
|||||||
|
16362 |
Irf1 |
interferon regulatory factor 1 |
0.59 |
0.98 |
1.00 |
7.28 |
3.78 |
|
|
|||||||
|
20846 |
Stat1 |
signal transducer and activator of transcription 1 |
0.57 |
0.81 |
1.00 |
6.84 |
4.02 |
|
|
|||||||
|
20846 |
Stat1 |
signal transducer and activator of transcription 1 |
0.66 |
0.97 |
1.00 |
6.17 |
2.79 |
|
|
|||||||
|
15957 |
Ifit1 |
interferon-induced protein with tetratricopeptide repeats 1 |
0.79 |
1.03 |
1.00 |
5.77 |
4.15 |
|
|
|||||||
|
60440 |
Iigp1 |
interferon inducible GTPase 1 |
0.77 |
1.00 |
1.00 |
4.19 |
3.00 |
|
|
|||||||
|
15976 |
Ifnar2 |
Interferon (alpha and beta) receptor 2 |
1.10 |
1.60 |
1.00 |
3.73 |
2.19 |
|
|
|||||||
|
Irf5 |
interferon regulatory factor 5 |
0.53 |
0.70 |
1.00 |
3.47 |
2.02 |
|
|
|
|||||||
|
|
|||||||
|
Others |
|||||||
|
|
|||||||
|
17071 |
Ly6f |
Lymphocyte antigen 6 complex, locus F |
0.56 |
0.73 |
1.00 |
8.56 |
2.68 |
|
|
|||||||
|
11629 |
Aif1 |
allograft inflammatory factor 1 |
0.90 |
1.33 |
1.00 |
8.46 |
2.62 |
|
|
|||||||
|
17067 |
Ly6c |
Lymphocyte antigen 6 complex, locus C |
1.24 |
1.22 |
1.00 |
7.35 |
5.27 |
|
|
|||||||
|
17067 |
Ly6c |
lymphocyte antigen 6 complex, locus C |
0.99 |
1.12 |
1.00 |
6.03 |
5.77 |
|
|
|||||||
|
17071 |
Ly6f |
lymphocyte antigen 6 complex, locus F |
0.80 |
0.89 |
1.00 |
5.66 |
5.01 |
|
|
|||||||
|
20343 |
Sell |
selectin, lymphocyte |
0.61 |
0.79 |
1.00 |
5.03 |
3.91 |
|
|
|||||||
|
76281 |
Tax1bp1 |
Tax1 (human T-cell leukemia virus type I) binding protein 1 |
1.01 |
1.51 |
1.00 |
5.02 |
1.98 |
|
|
|||||||
|
230233 |
Ikbkap |
inhibitor of kappa light polypeptide enhancer in B-cells |
0.81 |
0.93 |
1.00 |
4.55 |
1.43 |
|
|
|||||||
|
110454 |
Ly6a |
lymphocyte antigen 6 complex, locus A |
0.96 |
0.98 |
1.00 |
4.13 |
2.42 |
|
|
|||||||
|
13025 |
Ctla2b |
Cytotoxic T lymphocyte-associated protein 2 beta |
0.68 |
1.20 |
1.00 |
4.12 |
3.40 |
|
|
|||||||
|
71966 |
Nkiras2 |
NFKB inhibitor interacting Ras-like protein 2 |
1.07 |
1.27 |
1.00 |
3.80 |
1.93 |
|
|
|||||||
|
17087 |
Ly96 |
lymphocyte antigen 96 |
1.13 |
1.43 |
1.00 |
3.77 |
1.44 |
|
|
|||||||
|
17069 |
Ly6e |
Lymphocyte antigen 6 complex, locus E |
0.77 |
1.15 |
1.00 |
3.28 |
1.87 |
|
|
|||||||
|
* In italic transcripts common to day 21 and 42; in bold those unique to each category |
|||||||
|
Worschech et al. BMC Genomics 2009 10:301 doi:10.1186/1471-2164-10-301 |
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