Ratio of FZD6 transcript levels in 2 46,XY normal males (N-003; N-015) and 46,XX strongly virilized females (P-103; P-105) compared with two 46,XX normal females (N-020; N-031) and two 46,XY females (P-019; P-033) by semi-quantitative RT-PCR. The y-axis reflects the ratios of expression levels of the normal male – and the strongly virilized DSD individuals, respectively, divided through the phenotypic female individuals (normal females and 46,XY-sex reversed females) as indicated. RT-PCR confirms higher expression of FZD6 in virilized individuals.
Holterhus et al. BMC Genomics 2009 10:292 doi:10.1186/1471-2164-10-292