BMC Genomics

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Open Access Database

7TMRmine: a Web server for hierarchical mining of 7TMR proteins

Guoqing Lu1,2, Zhifang Wang3, Alan M Jones4,5 and Etsuko N Moriyama6,7*

Author Affiliations

1 Department of Computer Science, University of Nebraska at Omaha, Omaha, NE 68182, USA

2 Department of Biology, University of Nebraska at Omaha, Omaha, NE 68182, USA

3 Department of Computer Science and Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588-0660, USA

4 Departments of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

5 Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

6 School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, NE 68588-0118, USA

7 Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE 68588-0118, USA

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BMC Genomics 2009, 10:275 doi:10.1186/1471-2164-10-275

Published: 19 June 2009

Additional files

Additional file 1:

Classifier performance on GPCRDB proteins. Classifiers were tested against the entire dataset of GPCRDB. The table summarizes the % positive identifications for each GPCR class as well as for two organisms (Homo sapiens and Drosophila melanogaster).

Format: PDF Size: 45KB Download file

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Open Data

Additional file 2:

Number of transmembrane regions predicted from GPCRDB proteins. Transmembrane regions were predicted from the entire GPCRDB proteins using two methods, Phobius and HMMTOP.

Format: PDF Size: 300KB Download file

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Open Data

Additional file 3:

7TMR candidate proteins identified from the Arabidopsis thaliana genome. 189 proteins (or 162 proteins excluding predicted alternative-splice products) were obtained by combining the results of eight classifiers and two TM-prediction methods.

Format: PDF Size: 79KB Download file

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Open Data

Additional file 4:

7TMR candidate proteins identified from the Oryza sativa genome. 84 proteins were obtained by combining the results of eight classifiers and two TM-prediction methods.

Format: PDF Size: 40KB Download file

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Open Data

Additional file 5:

7TMR candidate proteins identified from the Populus trichocarpa genome. 153 proteins were obtained by combining the results of eight classifiers and two TM-prediction methods.

Format: PDF Size: 47KB Download file

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Open Data