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Open AccessHighly AccessResearch article

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

Tatjana Haitina1 email, Robert Fredriksson1 email, Steven M Foord2 email, Helgi B Schiöth1 email and David E Gloriam2 email

1Department of Neuroscience, Functional Pharmacology, Uppsala University, BMC, Box 593, 751 24, Uppsala, Sweden

2GlaxoSmithKline Pharmaceuticals, New Frontiers Science Park, 3rd Avenue, Harlow CM19 5AW, UK

author email corresponding author email

BMC Genomics 2009, 10:24doi:10.1186/1471-2164-10-24

Published: 15 January 2009

Additional files

Additional file 1:

Comparative table of the GRAFS family receptors in dog, human, rat and mouse. A table listing the dog (cf), human (hs), rat (rn) and mouse (mm) GPCRs of the Glutamate, Rhodopsin, Adhesion, Frizzled and Secretin families. Pseudogenes are marked with a "P" in the column to the right of the respective species. When several species- or lineage-specific duplicates (paralogs) exist the paralog with the highest sequence identity has been given as the primary ortholog whereas the other genes are present on separate rows in the table and without a counterpart in the other species.

Format: XLS Size: 171KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

Dog GPCR amino acid sequences. Complete list of dog GPCR amino acid sequences and pseudogenes in FASTA format.

Format: TXT Size: 216KB Download file


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