BMC Genomics

official impact factor 4.21

Open Access Highly Access Methodology article

Systematic identification of transcription factors associated with patient survival in cancers

Chao Cheng1, Lei M Li2,3, Pedro Alves1 and Mark Gerstein1,4,5*

Author Affiliations

1 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA

2 Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA

3 Department of Mathematics, University of Southern California, Los Angeles, CA 90089, USA

4 Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA

5 Department of Computer Science, Yale University, New Haven, CT, USA

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BMC Genomics 2009, 10:225 doi:10.1186/1471-2164-10-225

Published: 15 May 2009

Additional files

Additional file 1:

Complete results for breast cancer. Spearman correlation coefficient between PWM activity and survival is calculated based on 98 samples from patients with breast cancer.

Format: XLS Size: 63KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 2:

Survival analysis of ER-positive and ER-negative breast cancer subgroups. The survival curves are estimated using the Kaplan-Meier method and the difference between subgroups is examined by the log-rank test.

Format: PDF Size: 10KB Download file

This file can be viewed with: Adobe Acrobat Reader

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Additional file 3:

Complete results for ER-positive breast cancer. Spearman correlation coefficient between PWM activity and survival is calculated based on 53 samples from patients with ER-positive breast cancer.

Format: XLS Size: 63KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 4:

Complete results for ER-negative breast cancer. Spearman correlation coefficient between PWM activity and survival is calculated based on 44 samples from patients with ER-negative breast cancer.

Format: XLS Size: 63KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 5:

Complete results for acute myeloid leukemia. Spearman correlation coefficient between PWM activity and survival is calculated based on 116 samples from patients with acute myeloid leukemia.

Format: XLS Size: 63KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data