Table 2

The overlap between KEGG pathway genes and hits/nonhits in the corresponding RNAi screen.

KEGG pathway

(#genes)

All hits

Experimentally validated hits

Top-ranked hits

All nonhits

Top-ranked nonhits

(RR > 0.9)

Top-ranked nonhits

(RR > 0.8)


Hh signaling pathway (23)

9

6

9

14

7

10


Wnt signaling pathway (65)

9

8

9

56

32

48


Each cell represents the overlap between KEGG pathway genes (rows) and all, or subsets of, hits/nonhits in the corresponding RNAi screen (columns). The hits/nonhits were ranked by NePhe score. The top-ranked hits (column 3) are of the same size as the experimentally validated hits (column 2).

Wang et al. BMC Genomics 2009 10:220   doi:10.1186/1471-2164-10-220

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