A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila

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Research article

Li Wang¹ , Zhidong Tu² and Fengzhu Sun¹^,3

¹Molecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089, USA

²Rosetta Inpharmatics, a wholly owned subsidiary of Merck & Co., Inc, 401 Terry Ave N, Seattle WA 98109, USA

³MOE Key Laboratory of Bioinformatics and Bioinformatics Division, TNLIST/Department of Automation, Tsinghua University, Beijing, PR China

author email corresponding author email

BMC Genomics 2009, 10:220doi:10.1186/1471-2164-10-220


Published:	12 May 2009

Additional file 1:

Supplementary materials. This file contains all the supplementary text, tables and figures.

Format: PDF Size: 729KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 2:

NePhe scores. This file contains the NePhe score results for both hits and nonhits of the 24 whole-genome RNAi screens.

Format: XLS Size: 7.7MB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 3:

R package NePhe. This file contains the source codes of the R package for computing NePhe scores.

Format: RAR Size: 8KB Download file