Gene set internal coherence in the context of functional profiling

doi:10.1186/1471-2164-10-197

BMC Genomics

Volume 10

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Research article

Gene set internal coherence in the context of functional profiling

David Montaner¹^,2 , Pablo Minguez¹ , Fátima Al-Shahrour¹ and Joaquín Dopazo¹^,2^,3

¹Department of Bioinformatics and Genomics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, E-46013, Spain

²Functional Genomics Node (INB), Centro de Investigación Príncipe Felipe (CIPF), Valencia, E-46013, Spain

³CIBER de Enfermedades Raras (CIBERER), Valencia, E-46013 Spain

author email corresponding author email

BMC Genomics 2009, 10:197doi:10.1186/1471-2164-10-197


Published:	27 April 2009

Additional files

Additional File 1:

Additional Figure 1. Coherence index values as a function of functional module size obtained for the three GO ontologies: Biological process (left), molecular function (center) and cellular component (right).

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Additional File 2:

Additional Figure 2. Relationship between the coherence index and its standard deviation for KEGG (up left), GO biological process (up right), molecular function (down left) and cellular component (down right).

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