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Open Access Research article

Gene set internal coherence in the context of functional profiling

David Montaner1,2, Pablo Minguez1, Fátima Al-Shahrour1 and Joaquín Dopazo1,2,3*

Author Affiliations

1 Department of Bioinformatics and Genomics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, E-46013, Spain

2 Functional Genomics Node (INB), Centro de Investigación Príncipe Felipe (CIPF), Valencia, E-46013, Spain

3 CIBER de Enfermedades Raras (CIBERER), Valencia, E-46013 Spain

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BMC Genomics 2009, 10:197 doi:10.1186/1471-2164-10-197

Published: 27 April 2009

Additional files

Additional File 1:

Additional Figure 1. Coherence index values as a function of functional module size obtained for the three GO ontologies: Biological process (left), molecular function (center) and cellular component (right).

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Additional File 2:

Additional Figure 2. Relationship between the coherence index and its standard deviation for KEGG (up left), GO biological process (up right), molecular function (down left) and cellular component (down right).

Format: JPEG Size: 187KB Download file

Open Data